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Analyze exact chemical formulas, molecular weights, pharmacokinetic clearance curves, and human randomized controlled trial (RCT) evidence tiers powered by NCBI PubChem.
Formula: C4H9N3O2 · H2O • CAS: 6020-87-7 • CID: 586
2-[carbamimidoyl(methyl)amino]acetic acid hydrateGold standard ergogenic aid. Over 500 peer-reviewed trials demonstrate increased intracellular phosphocreatine stores, elevating cellular ATP resynthesis during high-intensity anaerobic output.
149.15 g/mol
60 min
3 hrs
586
Loading (optional): 20g/day (4 x 5g) for 5-7 days. Maintenance: 3-5g daily indefinitely (no cycling required).
High bioavailability (>99%). Absorbed across intestinal brush border via CreaT1 / SLC6A8 sodium- and chloride-dependent cotransporters.
Deep dive into phosphocreatine cellular ATP physics, 20g loading vs 3g daily math, and kidney safety.