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Search active human clinical trials across the globe. Filter by medical condition, research phase (Phase 1–4), recruitment status, and sponsor to explore cutting-edge medical treatments.
A randomized, double-blind, placebo-controlled Phase 3 trial evaluating the efficacy and safety of tirzepatide 5mg, 10mg, and 15mg in participants with overweight or obesity without diabetes.
Assessing 68-week efficacy and safety of subcutaneous semaglutide 2.4 mg once weekly versus placebo for weight loss and cardiovascular metabolic risk markers in adults without type 2 diabetes.
Evaluating the long-term safety and glycemic efficacy of once-daily oral non-peptide GLP-1 receptor agonist orforglipron compared with active comparators.
Phase 3 study evaluating the safety and efficacy of donanemab (anti-amyloid plaque monoclonal antibody) in slowing clinical progression in early symptomatic Alzheimer disease.
Targeting Aging with Metformin (TAME): Investigating whether metformin delays the development or progression of age-related chronic diseases including cardiovascular disease and cancer.
Evaluating the reduction of hepatic steatosis and liver fibrosis in patients with biopsy-confirmed metabolic dysfunction-associated steatohepatitis (MASH).
Read our comprehensive patient & caregiver guide explaining study phase progression (Phase 1–4), placebo controls, safety monitoring boards, and how to verify eligible active trials.
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